李 兰 花

一、个人简介

李兰花，博士，副教授，流行病学教研室专职教师。主持国家自然科学基金青年基金项目和山东省自然科学基金面上项目各1项，以第一作者或通讯作者发表中英文论文20余篇，指导本科生获得国家级大学生创新训练项目1项、省级创新训练项目3项。目前带教研究生8名。邮箱：orchid8@sina.com。

二、研究方向

目前主要从事传染病媒介生物及空间流行病学相关研究。

三、代表性科研项目

1、活性氧在长角血蜱肠道共生菌抑制田鼠巴贝虫传播中的机制研究（81902095），国家自然科学基金青年基金项目，2020.01 - 2022.12，主持，20万元；

2、共生菌在镰形扇头蜱抗田鼠巴贝虫感染免疫作用中的分子机制研究（ZR2019MH093），山东省自然科学基金面上项目，2019.07-2022.06，主持，20万元；

3、我国毒蘑菇中毒事件的时空分布特征及基于机器学习的风险预测预警模型的构建，国家食品安全风险评估中心2022 年度科研联合攻关计划项目，2022.07-2025.06，主持，10万元。

四、代表性论文

1、Kai Liu, Jing Tan, Lu Xiao, Rui-Tai Pan, Xiao-Yan Yao, Fu-Yan Shi, Shi-Zhu Li, Lan-Hua Li. Spatio-temporal disparities of Clonorchis sinensis infection in animal hosts in China: a systematic review and meta-analysis. Infect Dis Poverty. 2023, 12(1):97（通讯作者）

2、Xiao-Yan Yao, Shao-Qi Yu, Na Tian, Fei Wang, Shi-Zhu Li, Lan-Hua Li. Nucleic Acid Prevalence of Zoonotic Babesia in Humans, Animals and Questing Ticks, a Systematic Review and Meta-Analysis. Trop Med Infect Dis. 2023,22;8(3):132（通讯作者）

3、Li Lan-Hua, Wang Jia-Zhi, Zhu Dan, Li Xi-Shang, Lu Yan, Yin Shou-Qin, Li Sheng-Guo, Zhang Yi, and Zhou Xiao-Nong. Detection of novel piroplasmid species and Babesia microti and Theileria orientalis genotypes in hard ticks from Tengchong County, Southwest China. Parasitology Research. 2020,119(4):1259-1269

4、Li Lan-Hua, Lv Shan, Lu Yan, Bi Ding-Qi, Guo Yun-Hai, Wu Jia-Tont, Yue Zhi-Yuan, Mao Guang-Yao, Guo Zhong-Xin, Zhang Yi, Tang Yun-Feng. Spatial structure of the microbiome in the gut of Pomacea canaliculata. BMC Microbiol. 2019,19(1):273

5、Li Lan-Hua, Zhang Yi, Wang Jia-Zhi, Li Xi-Shang, Yin Shou-Qin, Zhu Dan, Xue Jing-Bo, Li Sheng-Guo. High genetic diversity in hard ticks from a China-Myanmar border county. Parasit Vectors, 2018, 11(1): 469

6、Li Lan-Hua, Zhang Yi, Zhu Dan. Effects of antibiotic treatment on the fecundity of Rhipicephalus haemaphysaloides ticks. Parasit Vectors, 2018,11(1): 242

7、Li Lan-Hua, Zhang Yi, Zhu Dan, Zhou Xiao-Nong. Endosymbionts Alter Larva-to-Nymph Transstadial Transmission of Babesia microti in Rhipicephalus haemaphysaloides Ticks. Front Microbiol, 2018, 9: 1415

8、Li Lan-Hua, Zhu Dan, Zhang Chen-Chen, Zhang Yi, Zhou Xiao-Nong. Experimental transmission of Babesia microti by Rhipicephalus haemaphysaloides. Parasit Vectors, 2016, 9(1): 231

9、Li Lan-Hua, Zhou Xiao-Nong, Du Zun-Wei, Wang Xue-Zhong, Wang Li-Bo, Jiang Jin-Yong, Yoshikawa Hisao, Steinmann Peter, Utzinger Jurg, Wu Zhiliang, Chen Jia-Xu, Chen Shao-Hong, Zhang Ling. Molecular epidemiology of human Blastoeystis in a village in Yunnan province, China. Parasitol Int, 2007, 56(4): 281-286

10、Li Lan-Hua, Zhang Xiao-Ping, Lv Shan, Zhang Ling, Yoshikawa Hisao, Wu Zhiliang, Steinmann Peter, Utzinger Jueg, Tong Xiao-Mei, Chen Shao-Hong, Zhou Xiao-Nong. Cross-sectional surveys and subtype classification of human Blastocystis isolates from four epidemiological settings in China. Parasitol Res, 2007, 102(1): 83-90