王 团 伟
一、个人简介
王团伟，博士，副教授，硕士生导师，毕业于复旦大学公共卫生学院，劳动卫生与环境卫生学专业。现为中国毒理学会毒理学教育专业委员会委员、山东省公共卫生学会卫生毒理分会委员，山东省预防医学会卫生毒理分会委员。主持省部级课题2项、厅局级课题1项；以第一、通讯作者发表SCI论文10篇。承担本科生、研究生《预防医学》、《职业卫生与职业医学》、《环境卫生学》等课程的教学与实践。目前指导硕士研究生6名。邮箱：wangtuanwei@sdsmu.edu.cn。
二、研究方向
环境流行病学、环境毒理学。主要科研方向：1）重金属的遗传毒性及机制研究；2）新污染物的生殖毒性及表观遗传学机制；3）抗生素污染及可移动遗传原件传播规律研究。
三、代表性科研项目
1.DNA甲基化在职业铅接触致遗传损伤中的调控机制（ZR2022QH180），山东省自然科学基金青年基金，2023.01.01-2025.12.31，第一位，15万；
2.抗生素抗性基因（AMRs）在人群中的暴露特征及传播规律研究（LH2022GG07），国家食品安全风险评估中心2022年度科研联合攻关计划项目，2022.7-2025.6，第一位，10万；
3.DNMT1调控DNA损伤应答基因甲基化在环境铅暴露致遗传损伤中的作用机制研究（2022YX040），2022年潍坊市科技发展计划项目（医学类），2022.11-2025.12，第一位，1万；
4.DNA甲基化及其关联基因多态性在职业铅暴露致遗传损伤中的调控机制（2021BKQ），潍坊医学院A类博士科研启动基金，2022.01-2026.12，第一位，72万。
四、代表性论文
1.Chunyan Lang, Jiachun Tang, Guanghui Zhang, Yu Meng, William W Au, Zhao-Lin Xia, Tuanwei Wang(通讯作者). Comparison of sensitivity between blood parameters and a genotoxic biomarker at low blood Pb levels: A population-based study. Ecotoxicology and Environmental Safety. 2024 Sep 15;283:116796. doi: 10.1016/j.ecoenv.2024.116796.
2.Zhiyuan Han, Shiyang Gong, Yuting Tu, Chunyan Lang, Jiachun Tang, Tuanwei Wang(通讯作者), Zhao-Lin Xia. The Relationships Between Blood Pb Levels and Blood Pressure Among Lead-Exposed Workers in China: A Repeated-Measure Study. Journal of Occupational and Environmental Medicine, 2023Dec1;65(12):e759-e763.doi:10.1097/JOM.0000000000002974.
3. Tuanwei Wang(第一作者), Yu Meng, Yuting Tu, Guanghui Zhang, Kan Wang, Shiyang Gong, Yunxia Zhang, Tongshuai Wang, Anqi Li, David C. Christiani, William Au, Zhao-lin Xia. Associations between DNA methylation and genotoxicity among lead-exposed workers in China. Environmental Pollution 2022, 316:120528. doi:10.1016/j.envpol.2022.120528.
4. TuanweiWang(第一作者), Yuting Tu, Guanghui Zhang, Shiyang Gong, Kan Wang, Yunxia Zhang, Yu Meng, Tongshuai Wang, Anqi Li, David C. Christiani, William Au, Yiliang Zhu, Zhao-lin Xia. Development of a benchmark dose for lead-exposure based on its induction of micronuclei, telomere length changes and hematological toxicity. Environment International2020,145:106129.doi:10.1016/j.envint.2020.106129.
5. Tuanwei Wang(第一作者), Yuting Tu, Kan Wang, Shiyang Gong, Guanghui Zhang, Yunxia Zhang, Yu Meng, Tongshuai Wang, Anqi Li, Junpeng Cui, Huan Liu, Weifeng Tang, Jing Xi, Yiyi Cao, Yang Luan, David C. Christiani, William Au, Zhao-lin Xia. Associations of blood lead levels with multiple genotoxic biomarkers among workers in China: A population-based study. Environmental Pollution 2020, 273:116181. doi:10.1016/j.envpol.2020.116181.
6. Yiyi Cao, Tuanwei Wang(共同一作), Jing Xi, Guanghui Zhang, Tongshuai Wang, Weiying Liu, Xinyue You, Xinyu Zhang, Zhao-lin Xia, Yang Luan. PIG-A gene mutation as a genotoxicity biomarker in human population studies: An investigation in lead-exposed workers. Environmental and molecular mutagenesis 2020, 61(6):611-621.
7. Kan Wang, Tuanwei Wang(共同一作), Jie Xu, Yiliang Zhu, Le Jian, William Au, Zhao-lin Xia. Determination of benchmark dose based on adduct and micronucleus formations in formaldehyde-exposed workers. Int J Hyg Environ Health 2019, 222(5):738-743.
8. Kan Wang, Yu Meng, Tuanwei Wang(共同一作), Yuting Tu, Shiyang Gong, Guanghui Zhang, William Au, Zhao-lin Xia. Global and gene-specific promoter methylation, and micronuclei induction in lead-exposed workers: A cross-sectional study. Environ Mol Mutagen 2021,62(7):428-434.
9. Tuanwei Wang(第一作者), Hui Zhang, Lei Li, Wenjuan Zhang, Qi Wang, Wei Wang. Plasma cholinesterase activity is influenced by interactive effect between Omethoate exposure and CYP2E1 polymorphisms. J Environ Sci Health B 2021,56(5):477-482.
10. Tuanwei Wang(第一作者), Sihua Wang, Xiaoran Duan, Xiaolei Feng, Pengpeng Wang, Wu Yao, Yongjun Wu, Feifei Feng, Songcheng Yu, Yiming Wu, Wei Wang. Application of created restriction site PCR-RFLP to identify POT1 gene polymorphism. Biochemistry (Moscow) 2016, 81(6):624-627.