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孙金月个人简介
发布者:ggxy    发表时间:2021-03-24

孙 金 月

一、个人简介

孙金月,博士,研究员,泰山学者特聘专家,博士生导师。兼农业农村部新食品资源加工重点实验室学术委员会副主任、山东省食品安全地方标准审评委员会委员、《山东农业科学》编委等。近年主持国家重点研发计划项目、国家自然科学基金面上项目、山东省自然科学基金重大基础研究项目、山东省重大科技创新工程项目等18项;发表论文90余篇,其中SCI 论文60余篇;授权国家发明专利13项、国际发明专利1项、国家实用新型专利11项,授权国家软件著作权11项;制定山东省地方标准1项;获国家重点科技攻关计划重大科技成果、山东省科技进步二等奖、国家商业联合会科技进步二等奖等成果奖励6项。目前正在培养的研究生6人。邮箱:moon_s731@hotmail.com

二、研究方向

生物活性物质与功能食品。主要从事药用植物、食药同源、新食品资源等原料中生物活性成分的高效制备、结构鉴定、功能评价、分子机理、靶向递送与产品开发研究,针对高尿酸血症、高血糖、高血脂、肿瘤等慢性疾病人群,研制相关的营养健康及功能产品(功能食品、中间体、原料药等)。

三、代表性科研项目

1、基于医养健康的绿色资源技术集成创新与示范(2021SFGC0904),山东省重点研发计划(重大科技创新工程)项目,2021.10-2024.12,第一位,2201万元。

2、腰果高效加工及副产物综合利用关键技术研究(2021YFE0109200),国家重点研发计划项目,2021.07-2023.06,第一位,101万元。

3降尿酸功能食品精深加工关键技术研究与开发(2019JZZY020612),山东省重大科技创新工程项目,2019.11-2021.12,第一位,350万元。

4、琉璃苣种子γ-亚麻酸高效合成的分子与调控机制研究(31571708),国家自然科学基金面上项目,2016.01-2019.12,第一位,71.844万元。

5、微生物源生物拮抗菌剂的研发(2015BAD16B02),国家科技支撑计划课题,2015.04-2018.03,第一位,650万元。

四、代表性论文

1Sheng-Nan Yuan, Mu-xuan Wang, Jin-Long Han, Cai-Yun Feng, Meng Wang, Min Wang, Jin-Yue Sun通讯作者, Ning-yang Li*, Jesus Simal-Gandara*, Chao Liu*. Improved colonic inflammation by nervonic acid via inhibition of NF-κB signaling pathway of DSS-induced colitis mice, Phytomedicine, 2023, 112: 154702.

2Bendong Yang, Meiling Xin, Shufei Liang, Yuhong Huang, Jingda Li, Chao Wang, Chao Liu, Xinhua Song*, Jinyue Sun通讯作者, Wenlong Sun*. Naringenin ameliorates hyperuricemia by regulating renal uric acid excretion via the PI3K/AKT signaling pathway and renal inflammation through the NF-κB signaling pathway, Journal of Agricultural and Food Chemistry, 2023, 71: 1434-1446.

3Bendong Yang, Meiling Xin, Shufei Liang, Xiaoxue Xu, Tianqi Cai, Ling Dong, Chao Wang, Meng Wang, Yuting Cui, Xinhua Song*, Jinyue Sun通讯作者, Wenlong Sun*. New insight into the management of renal excretion and hyperuricemia: Potential therapeutic strategies with natural bioactive compounds, Frontiers in Pharmacology, 2022, 13: 1026246.

4Nan Chen, Qing Wang, Mu-Xuan Wang, Ning-yang Li, Annabelle V. Briones , L. Cassani, M.A. Prieto*,, Maricar B. Carandang, Chao Liu*, Chun-Mei Gu*, Jin-Yue Sun通讯作者. Characterization of the physicochemical, thermal and rheological properties of cashew kernel starch, Food Chemistry: X,2022, 15: 100432.

5Jia-shu Chen, Mu-xuan Wang, Min-min Wang, Yu-kai Zhang, Xu Guo, Ying-ying Chen, Meng-qi Zhang, Jin-yue Sun通讯作者, Yu-fa Liu*, Chao Liu*. Synthesis and biological evaluation of geniposide derivatives as inhibitors of hyperuricemia, inflammatory and fibrosis, European Journal of Medicinal Chemistry, 2022, 237: 114379.

6Yu-kai Zhang, Jia-shu Chen, Min-min Wang, Chuan-zeng Wang, Mu-xuan Wang, Zhen Wang, Qin-liang Yang, Bin Sun,*, Jin-yue Sun通讯作者, Yu-fa Liu*, Chao Liu*. Synthesis and bioactivity evaluation of novel nuciferine derivatives with antihyperuricemia and nephroprotective effects, Bioorganic Chemistry, 2022, 126: 105916.

7Mu-xuan Wang, Min-min Wang, Chao Liu*, Jia-shu Chen, Xu Guo, Jian-shu Liu, Meng-qi Zhang, Jing Zhang, Jin-yue Sun通讯作者, Zhi-xin Liao*. A geniposide-phospholipid complex ameliorates posthyperuricemia chronic kidney disease induced by inflammatory reactions and oxidative stress, European Journal of Pharmacology, 2022, 930: 175157.

8Yanxia Liu, Chao Liu, Peng Gao, Yuhao Wu, Xiaorui Wang, Xiaoming Lu, Jinyue Sun通讯作者, Jianbo Xiao*, Jesus Simal-Gandara*, Ningyang Li*. The formation of antibiotic-resistance genes in bacterial communities during garlic powder processing, Frontiers in Nutrition, 2021, 9: 800932.

9Xiu-zheng Gao, Xu-tao Lv, Rui-rui Zhang, Yang Luo, Mu-xuan Wang, Jia-shu Chen, Yu-kai Zhang, Bin Sun*, Jin-yue Sun通讯作者, Yu-fa Liu*, Chao Liu*. Design, synthesis and in vitro anticancer research of novel tetrandrine and fangchinoline derivatives, Bioorganic Chemistry, 2021, 109: 104694.

10Muxuan Wang, Jiashu Chen, Ruirui Zhang, Xinyan Guo, Daxia Chen, Xu Guo, Yingying Chen, Yuhao Wu, Jinyue Sun通讯作者, Yufa Liu*, Chao Liu*. Design, synthesis and bioactive evaluation of geniposide derivatives for antihyperuricemic and nephroprotective effects, Bioorganic Chemistry, 2021, 116: 105321.