欢迎访问山东第二医科大学公共卫生学院
姜 大 峰
一、个人简介
姜大峰,博士,主任技师,现为山东省疾病预防控制中心科研教育部副主任。中国营养学会微量元素营养分会第八届委员会委员、山东省公共卫生学会医学伦理学分会第一届委员会副主任委员、山东省微量元素科学研究会分析测试专业委员会第八届副主任委员、山东大学和山东第一医科大学研究生合作导师。目前带教研究生3名。主持完成国家自然科学青年基金项目1项,省医药卫生科技发展计划项目1项,参与省医药卫生科技发展计划项目和省中医药科技项目8项;发表SCI论文37篇,其中第一/通讯作者23篇;发表中文期刊论文17篇。获2022年度山东医学科学技术奖三等奖1项(第1位),2022年度山东预防医学科学技术奖1项(第2位);获“齐鲁卫生与健康杰出青年人才”“ 全省抗击疫情优秀志愿者”“优秀援疆人才”等荣誉称号。电子邮箱:sdcdcchem@163.com
二、研究方向
研究方向为纳米生物传感器的构建与生物医学、食品安全检测分析应用。基于功能核酸识别和信号放大策略,构建新型纳米生物传感器用于病毒相关mRNA/DNA和疾病生物标志物的超灵敏检测和食品中化学有害因素的灵敏、快速检测。
三、代表性科研项目
1、基于量子点作为元素标记的ICP-MS技术用于高灵敏度多组分真菌毒素定量方法研究(21705095),国家自然科学基金青年基金项目,2018.01-2020.12,第一位,24万元;
2、山东省市售禽畜肉中重金属元素含量分析及人群暴露健康风险评估(202112061045),山东省医药卫生科技发展计划项目,2022.01-2023.12,第一位,2万元;
3、基于质谱辨识技术的中药外源性污染物风险评估及 药效成分相关性研究(M-2023251),山东省中医药科技项目面上项目,2023.08-2025.07,第二位,2万元;
4、鲁西南高碘地区水源水中微量元素含量调查与人群暴露健康风险评估(202312061402),山东省医药卫生干科技项目重点项目,2024.01-2025.12,第三位,2万元。
四、代表性论文
1、Yuxin Wang, Lijun Shaob, Zhigang Zhao, Chao Huang, Yanni Jiao, Dapeng Sun, Rui Liu, Dafeng Jiang* (通讯作者), Xibao Gao* (通讯作者). Simultaneous detection of dual microRNAs related to EV71 using ,ICP-MS based on metal nanoparticle labeling with hybridization chain reaction, Analytica Chimica Acta (SCI, IF = 6.2), 2024, 1294:342272.
2、Chuan Qin, Xiaolin Wang, Lei Du, Luping Yang, Yanni Jiao, Dafeng Jiang*(通讯作者), Xinxin Zhang, Tianliang Zhang, Xibao Gao*(通讯作者). Heavy metals in meat products from Shandong, China and risk assessment. Food Additives Contaminants: Part B. (SCI, IF = 2.9), 2024, 17:56-65.
3、Tianran Zhang, Chao Huang, Yanni Jiao, Lijun Shao, Dafeng Jiang* (通讯作者), Fenghua Li, Wei Li, Xibao Gao* (通讯作者). ICP-MS and fluorescence dual-mode detection of ZIKV-RNA based on quantum dot labeling with hybridization chain reaction. Talanta (SCI, IF = 6.1), 2024, 269:125463.
4、Zhijie Chu, Nannan, Zhu, Lijun Shao, Hongxia Xu, Jin Li, Xiaolin Wang, Yanni Jiao, Dafeng Jiang* (通讯作者),Peimin Yang. Occurrence of 8 trace elements in Rhizoma Cibotii from China and exposure assessment. Environmental Science and Pollution Research (SCI, IF = 5.8), 2023, 30:115907–115914.
5、Chao Huang, Guohong Shen, Shengyong Ding, Ailing Kan, Dafeng Jiang*(通讯作者), Wei Jiang*(通讯作者). Primer-template conversion-based cascade signal amplification strategy for sensitive and accurate detection of polynucleotide kinase activity. Analytica Chimica Acta (SCI, IF = 6.2), 2021, 1187: 339139.
6、Chao Huang, Xiaowen Xu, Dafeng Jiang* (通讯作者), Wei Jiang* (通讯作者). Binding mediated MNAzyme signal amplification strategy for enzyme-free and label-free detection of DNA-binding proteins. Analytica Chimica Acta (SCI, IF = 6.2), 2021, 1166: 338560.
7、Jing Zhu*(通讯作者), Xia Liu, Jinxue Zheng, Dafeng Jiang*(通讯作者). Tuning the conformation of G-quadruplexes by sodium and potassium ions: application to photometric and fluorometric determination of amyloid β(1–40). Microchimica Acta (SCI, IF = 5.7), 2021, 188:98.
8、Dafeng Jiang, Chao Huang, Lijun Shao, Xiaolin Wang, Yanni Jiao, Wei Li, Jindong Chen*(通讯作者), Xiaowen Xu*(通讯作者). Magneto-controlled aptasensor for simultaneous detection of ochratoxin A and fumonisin B1 using inductively coupled plasma mass spectrometry with multiple metal nanoparticles as element labels. Analytica Chimica Acta (SCI, IF = 6.2), 2020, 1127:182-189.
9、Xiaolin Wang, Shufan Wang, Fenghua Li, Renpeng Li*(通讯作者), Jing Zhu, Jindong Chen, Wei Li, Dafeng Jiang*(通讯作者). Occurrence of polycyclic aromatic hydrocarbons in youtiao and exposure assessment from Shandong Province, China. Food Control (SCI, IF = 6.0), 2020, 111: 107049.